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In vitro sensitivity to ganciclovir of homotypic and heterotypic spheroids. A, ganciclovir sensitivity of spheroids made of Mel-TK cells alone or mixed with Mel-EGFP cells. B, ganciclovir sensitivity of spheroids made of Mel-(Δ10)-TK alone or mixed with Mel-EGFP cells. C, ganciclovir sensitivity of spheroids made of melanoma cells expressing TK mixed with WI-38 fibroblasts. or BAEC.
