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. 2009 Sep;128(1):114–122. doi: 10.1111/j.1365-2567.2009.03098.x

Figure 3.

Figure 3

Immune mediators in glomeruli of mice with glomerulonephritis. (a) There were fewer macrophages and CD4+ cells in glomeruli of CD100−/− mice and (b, c) reduced glomerular deposition of both (b) immunoglobulin G (IgG) and (c) C3 in CD100−/− mice. CD100+/+ and CD100−/− mice immunized with and injected with normal sheep globulin did not develop significant glomerular leucocyte infiltrates (hatched bars). **P< 0·005; ***P< 0·0005, unpaired t-test. c/gcs, cells per glomerular cross-section.