Fig. 4.

Optical images of complex nanochannels (A) and manipulation of a single DNA molecule along a straight nanochannel (B). (A) Nanofluidic representations of “nano” and “NBTC” (the logo of the Nanobiotechnology Center from Cornell University). Complex nanofluidic networks are possible with this technique. All these nanochannels are formed with at least one axis in nanometer regime (Scale bar, 100 and 50 μm, respectively). For a demonstration purpose, each letter is taken individually and then combined together. (B) Electrophoretic migration of the λ-DNA in a straight nanochannel by 40 V cm^-1 (0.5-s interval between the images.) Electric field is represented by E (Scale bar, 5 μm).