Fig. 3.

Relaxation behavior of ATRA differentiated APL cells before and after exposure to paclitaxel. The relaxation of differentiated APL cells after cessation of stress is decreased when treated with paclitaxel (TAX). (filled circles) APL cells treated with ATRA (n = 44), (open squares) APL cells treated with ATRA and paclitaxel (n = 56). The duration of stress application is indicated by the black bar on the time axis. Data show mean ± SEM. Insets show fluorescence images of the microtubule organization in both groups of cells.