Table 4.
Pregnancies by time after donation
| All | Pre- donation pregnancies only | Post-donation pregnancies only | Both pre- and post-donation pregnancies | |
|---|---|---|---|---|
| Donors with ≥ 1 pregnancy | 1085 | 846 | 141 | 98 |
| Total number of pregnancies | 3213 | 2519 | 317 | 377 |
| Age at donation, years | 39.7(11.7) | 43.7(9.7) | 23.8(4.7) | 28.2(5.1)* |
| Age at first pregnancy, years | 23.9(5.1) | 23.2(4.6) | 28.8(5.5) | 22.9(4.0)* |
| Time from 1st pregnancy to survey, years | 12.1(8.2) | 16.2(7.1) | 2.5(3.2) | 5.4(4.9) |
| Pregnancies/donor | ||||
| 1 | 5.0% | 4.8% | 12.3% | 0% |
| 2 | 21.8% | 20.9% | 38.5% | 13.8% |
| ≥ 3 | 73.2% | 74.3% | 49.2% | 86.2% |
| Creatinine at donation1 (mg/dL) | 0.84(0.13) | 0.84(0.13) | 0.85(0.13) | 0.81(0.13)† |
| MDRD GFR at donation1 | 83.5(17.9) | 82.1(17.9) | 90.0(16.1) | 92.2(16.3)* |
| Weight at donation2 (kg) | 69.0(12.4) | 69.6(12.3) | 63.9(12.9) | 66.6(12.6)* |
| BMI3 | 25.7(4.2) | 25.9(4.1) | 23.6(4.4) | 24.9(4.5)* |
| White | 97.0% | 96.9% | 98.4% | 96.8% |
| Relationship to recipient | ||||
| Related | 82.8% | 79.6% | 96.2% | 93.1% |
| Cause of recipient kidney disease | ||||
| Diabetes | 35.9% | 37.9% | 28.7% | 28.4% |
| Polycystic kidney disease | 6.0% | 6.9% | 2.5% | 2.9% |
| Glomerular disease | 16.3% | 15.1% | 25.6% | 16.5% |
| Hypertension | 2.9% | 2.9% | 3.5% | 2.7% |
| Other | 38.9% | 37.2% | 39.8% | 49.6% |
*
p < 0.0001
†
p= 0.0133
MDRD GFR = Modification of Diet in Renal Disease Glomerular Filtration Rate in mL/min/1.73m2.Missing values:
1
Serum creatinine and GFR at time of donation – 26.3%
2
Weight at donation – 52.6%
3
BMI – 54.3%