Cross-sectional soma areas of SNB motoneurons of normal controls and saporin-injected animals that were either untreated (SAP), or treated with testosterone (SAP+T), estradiol (SAP+E), or DHT (SAP+DHT). Following saporin-induced motoneuron death, the average soma area of surviving nearby motoneurons decreased by approximately 18%. Treatment with either testosterone or DHT attenuated this decrease, but treatment with estradiol was ineffective. Bar heights represent means ± SEM. * indicates significantly different from normal controls.