Skip to main content
. Author manuscript; available in PMC: 2010 Feb 27.
Published in final edited form as: Circ Res. 2009 Jan 15;104(4):466–475. doi: 10.1161/CIRCRESAHA.108.184846

Figure 7. Jagged1 expression is reduced in the absence of Notch3 in vivo.

Figure 7

Retinas isolated from Notch3 null (Notch-/-) and heterozygous (Notch+/-) mice at postnatal day 15 were immunostained to detect Jagged1 protein (green). An endothelial-specific lectin (red) was used to highlight the vasculature. Confocal images were taken at (A) 400× and (B) 630× (zoom2) magnification and pixel intensity of Jagged1 staining was quantified (C). Graph represents average Jagged1 expression from 8 null and 8 heterozygous retinas. * P = 0.0004.