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Structures of cinchona alkaloids and quinolines and their effects on melanin synthesis in melan-a cells
| Compound | Structure | Inhibition | |
|---|---|---|---|
| At 1 µM | At 5 µM | ||
| % | |||
| Cinchonidine |
|
25.0 | 35.7 |
| Hydrocinchonine |  |
24.0 | 37.3 |
| Hydroquinidine |  |
30.9 | 52.3 |
| Hydroquinidine 4-chlorobenzoate |  |
10.0 | 25.5 |
| Hydroquinine |  |
30.5 | 67.5 |
| Hydroquinine hydrobromide hydrate |  |
26.8 | 67.4 |
| N-Benzylcinchonidinium chloride |  |
9.6 | 16.4 |
