Abstract
The present study was done to determine whether so-called nontypable (NT) group B streptococci from human sources possess as yet unrecognized type antigens. Antisera were raised in rabbits against several NT strains and then tested with hydrochloric acid extracts of 53 NT group B streptococci. One serum was strain specific, another was nonspecific in that it contained only R-protein antibodies, and a third (NT1), although apparently type specific, reacted with only five strains. These results do not justify using NT1 serum in the group B typing system.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Lancefield R. C., McCarty M., Everly W. N. Multiple mouse-protective antibodies directed against group B streptococci. Special reference to antibodies effective against protein antigens. J Exp Med. 1975 Jul 1;142(1):165–179. doi: 10.1084/jem.142.1.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
- OUCHTERLONY O. Diffusion-in-gel methods for immunological analysis. Prog Allergy. 1958;5:1–78. [PubMed] [Google Scholar]
- PATTISON I. H., MATTHEWS P. R., HOWELL D. G. The type classification of group-B streptococci, with special reference to bovine strains apparently lacking in type polysaccharide. J Pathol Bacteriol. 1955 Jan-Apr;69(1-2):51–60. [PubMed] [Google Scholar]
- Wilkinson H. W. Comparison of streptococcal R antigens. Appl Microbiol. 1972 Oct;24(4):669–670. doi: 10.1128/am.24.4.669-670.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson H. W., Eagon R. G. Type-specific antigens of group B type Ic streptococci. Infect Immun. 1971 Nov;4(5):596–604. doi: 10.1128/iai.4.5.596-604.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wilkinson H. W., Facklam R. R., Wortham E. C. Distribution by serological type of group B streptococci isolated from a variety of clinical material over a five-year period (with special reference to neonatal sepsis and meningitis). Infect Immun. 1973 Aug;8(2):228–235. doi: 10.1128/iai.8.2.228-235.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]