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. Author manuscript; available in PMC: 2009 Sep 21.
Published in final edited form as: J Neuroimmunol. 2007 Jan 23;184(1-2):180–187. doi: 10.1016/j.jneuroim.2006.12.007

Figure 2.

Figure 2

Leukocyte subsets in spinal cord of control and CD11d-/- deficient mice with EAE are identical. Leukocytes isolated from spinal cords of control and CD11d-/- mice as described in Materials and Methods were immunostained for CD4, CD8 and CD45. A) The level of CD45+ cells infiltrating the spinal cords of wild type (n=5) and CD11d-/- (n=6) mice 10 days post-immunization are identical. B) The percentage of CD4+ T cells in the spinal cords of wild type and CD11d-/- mice at days 10 (n=5 and 6, respectively) and 21 (n=4 and 5, respectively) post-immunization were nearly identical (upper left quadrant in each panel). The percentage of CD8+ T cells is modestly elevated in CD11d-/- mice at day 21 post-immunization compared to wild type mice (lower right quadrant). The results shown are from cells pooled within each group of mice and a representative experiment is shown.