Table 2.
Changes in expression of β2-integrins on T cells and macrophages in CD11d-deficient mice during EAE
T cells | |||
---|---|---|---|
CD11aA | CD11b | CD11c | |
Spleen (WT) | 25 ± 0.78 | 6.8 ± 1.8 | 1.7 ± 1 |
Spleen (CD11d-/-) | 17 ± 5.5 | 5.4 ± 0.6 | 2.7 ± 0.6 |
Lymph node (WT) | 48 ± 5.9 | 4.9 ± 0.57 | 3.2 ± 1.5 |
Lymph node (CD11d-/-) | 45 ± 9.7 | 5.6 ± 1.6 | 3.3 ± 1.4 |
Macrophages | |||
CD11a | CD11b | CD11c | |
Spleen (WT) | 15 ± 1.9 | B16 ± 0.9 | C10± 1.1 |
Spleen (CD11d-/-) | 13 ± 1.9 | 13 ± 0.9 | 4.4 ± 2.0 |
Lymph nodes (WT) | 2.6 ± 0.7 | 2.3 ± 1.0 | 1.5 ± 0.9 |
Lymph nodes (CD11d-/-) | 2.4 ± 1.3 | 2.0 ± 0.9 | 2.1 ± 1.7 |
Data are presented as the mean ± S.D. from three mice.
Significantly different compared to spleens from CD11d-/- mice, p=0.02.
Significantly different compared to spleens from CD11d-/- mice, p=0.01.