Table 1.
Aspects | Avian flu65–72 | Swine flu 73–85 |
---|---|---|
1. Pathogenic virus | H5N1 influenza virus. | Atypical H1N1 influenza virus. |
2. Related animal | Avian. | Swine. |
3. Disease burden | High fatality. | No high fatality. |
4. Pandemic | No. | Yes (in 2009). |
5. Human to human transmission | No evidence. | Strong evidence. |
6. Vertical transmission | No evidence. | No evidence. |
7. Clinical manifestation | Similar to classical influenza with some interesting atypical manifestations (such as diarrhea). | Similar to classical influenza with some interesting atypical manifestations (such as nonfebrile illness). |
8. Viral receptor in human beings | Can be seen in lower respiratory tract. | Can be seen in upper respiratory tract. |
9. Vaccine | Not available. | Has been manufactured and approved by the US FDA.86 |
10. Treatment by antiviral drug | Needed, usually with oseltamivir, but there are few good outcomes. | Suggested, usually with oseltamivir, good outcomes. |
Abbreviation: FDA, US Food and Drug Administration.