Table 1.
Mean detectable concentrations of circulating hormones and metabolites at the time of tissue collection in cows maintained under mild or severe NEB
| MNEB | SNEB | P | ||
|---|---|---|---|---|
| No. cows | 5 | 6 | ||
| Days postpartum | 14±0.73 | 14±0.68 | ||
| Energy | Net EB, UFL/day | −1.7±1.17 | −6.1±1.03 | 0.018 |
| Endocrine | IGF-I, ng/ml | 51.4±10.33 | 10.6±1.09 | 0.002 |
| Insulin, μIU/ml | 0.2±0.07 | 0.1±0.02 | 0.12 | |
| PGFM, pg/ml | 34.0±8.72 | 55.0±17.65 | 0.34 | |
| Cortisol, ng/ml | 13.2±5.80 | 5.5±1.61 | 0.24 | |
| Estradiol, pg/ml | 2.2±0.33 | 1.6±0.24 | 0.14 | |
| Metabolism | Glucose, mmol/l | 4.1±0.15 | 2.7±0.15 | <0.001 |
| NEFA, mmol/l | 0.3±0.05 | 1.4±0.14 | <0.001 | |
| BHB, mmol/l | 0.5±0.09 | 3.7±0.20 | <0.001 | |
| SAA, mg/ml | 62±37.1 | 133±29.2 | 0.16 |
Values are means ± SE. EB, energy balance; MNEB, mild negative energy balance; SNEB, severe negative energy balance; UFL, unité fourragère lait; IGF-I, insulin like-growth factor-I; PGFM, 13,14-dihydro-15-keto-prostaglandin F2α; NEFA, nonesterified fatty acid; BHB, β-hydroxybutyrate; SAA, circulating serum amyloid A.