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(A) ALP activity in femur. (B) ALP activity in tibia. Nonsignificant increase in HLS and HLS + P.
Notes: *Indicates significant difference between: 1) control and HLS, 2) HLS and HLS + N, 3) HLS and HLS + P + N.
Abbreviations: ALP, alkaline phosphatase; HLS, hind-limb suspension; HLS + N, hind-limb suspension + nanoparticle (Si-Hap); HLS + P, hind-limb suspension + PEMF; HLS + P + N, hind-limb suspension + PEMF + nanoparticle; PEMF, pulsed electromagnetic field.
