Fig. 5.

The ultrastructure of the colchicine-treated Drosophila mitotic kinetochore. a, b Serial sections through two individual kinetochores from S2R+ cells treated with colchicine to depolymerize MTs. In the absence of MTs, the Drosophila kinetochore reveals a well-defined electron-dense outer layer with a hemispherical shape (brackets and arrowheads) that extends from a poorly defined internal region. Scale bar=200 nm