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. Author manuscript; available in PMC: 2010 Jul 15.
Published in final edited form as: Bioorg Med Chem. 2009 May 8;17(14):5318–5324. doi: 10.1016/j.bmc.2009.05.008

Table 1. Examples of differences in HIV-1 IN inhibitory potencies for enantiomeric α-methylbenzyl amides.

graphic file with name nihms116460f4.jpg

No. Structure IC50 (μM) IC50 (μM)
1 graphic file with name nihms116460t1.jpg 24a >300a
2 graphic file with name nihms116460t2.jpg 0.50b 5.00b
3 graphic file with name nihms116460t3.jpg 2.05c 1.05c
a

Taken from reference 15.

b

Taken from reference 17.

c

Taken from reference 14.