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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Aug;15(8):971–981. doi: 10.1016/j.bbmt.2009.04.015

Table 5.

Number of Subjects Needed to Achieve 80% Power for Detecting an Association with 100 day Mortality for the Six Most Frequent HLA-A Disparities in HLA-B, -C, and -DRB1 Matched Pairs*

HLA-A Mismatch Number of
Mismatches in
4,226 Subjects		 Number
Required for
80% Power		 Total Number of
Subjects Required to
Achieve 80% Power
A*0201:0205 27 72 11,269
A*0301:0302 15 4,687 1,320,484
A*0201:0206 15 39 10,988
A*0201:6801 11 43 16,520
A*0101:1101 11 2,653 1,019,234
A*0101:0201 9 2,014 945,685
A*2402:2403 8 30 15,848
*

Using the difference observed between each group and an 8/8 match.