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. 2003 Feb 10;88(3):470–477. doi: 10.1038/sj.bjc.6600719

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Copyright © 2003 Cancer Research UK

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HPLC separation of butanol-extracted, ³²P-postlabelled DNA adducts in MCF-7 (A and B), MDA-MB-435 (C and D) and IGROV-1 (E and F) cells following exposure to 1 μM (A, C and E) and 10 μM Phortress (B, D and F) in vitro. MCF-7 and MDA-MB-435 cells were exposed to drug for 72 h. DNA adducts generated in IGROV-1 cells were analysed after 24 h treatment.