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. 2003 Feb 10;88(3):455–462. doi: 10.1038/sj.bjc.6600791

Table 2. Enhanced sensitivity to etoposide and doxorubicin in serum-free media.

  %G0–G1 %S %G2–M
Media alone      
 Parental 54 36 10
 wtCD26 55 34 11
Etoposide (0.25 μM)      
 Parental 51 30 19
 wtCD26 34 23 43
Etoposide (0.50 μM)      
 Parental 36 28 36
 wtCD26 18 18 64
Doxorubicin (0.10 μM)      
 Parental 43 30 27
 WtCD26 31 20 49
Doxorubicin (0.25 μM)      
 Parental 36 23 41
 wtCD26 14 12 74

Following pretreatment with AIM V serum-free media at 37°C for 24 h, wtCD26 Jurkat transfectants and parental cells were incubated at 37°C in serum-free media with etoposide or doxorubicin for 24 h. Cells were then harvested and cell cycle analyses were performed with PI staining. Data are representative of three separate experiments.