Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2009 Sep 21.

Published in final edited form as: Methods Enzymol. 2006;410:279–299. doi: 10.1016/S0076-6879(06)10013-0

Identification of the DNA binding site motif from the significantly bound spots. (a) Distribution of ratios of PBM data, normalized by SYBR Green I data, for the yeast TF Rap1 bound to yeast intergenic microarrays. The arrow indicates those spots passing a P-value cutoff of 0.001 after correction for multiple hypothesis testing. Indicated in dark gray are spots with an exact match to a sequence belonging to the PBM-derived binding site motif. (b) Sequence logo (Schneider and Stephens, 1990) of the PBM-derived motif for the yeast transcription factor Rap1. (Reproduced from (Mukherjee et al., 2004) with permission from Nature Publishing Group.)

Identification of the DNA binding site motif from the significantly bound spots. (a) Distribution of ratios of PBM data, normalized by SYBR Green I data, for the yeast TF Rap1 bound to yeast intergenic microarrays. The arrow indicates those spots passing a P-value cutoff of 0.001 after correction for multiple hypothesis testing. Indicated in dark gray are spots with an exact match to a sequence belonging to the PBM-derived binding site motif. (b) Sequence logo (Schneider and Stephens, 1990) of the PBM-derived motif for the yeast transcription factor Rap1. (Reproduced from (Mukherjee et al., 2004) with permission from Nature Publishing Group.)