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Kinetic parameters for inhibition of MMPs by inhibitor 2
| 10−4 kon (per m per second) |
103 koff (per second) |
Ki (nm) | |
|---|---|---|---|
| MMP-2 | 4.5 ± 0.4 | 1.0 ± 0.2 | 23 ± 5 |
| MMP-9 | 2.1 ± 0.2 | 0.11 ± 0.10 | 5 ± 1 |
| MMP-14cat | 145 ± 10 | ||
| MMP-3cat | 600 ± 30 | ||
| MMP-7 | 18200 ± 3000 | ||
| MMP-1cat | 140000 ± 7000 |
MMP, matrix metalloproteinase.
