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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Curr Opin Pharmacol. 2009 Jun 29;9(4):462–469. doi: 10.1016/j.coph.2009.05.007

Figure 1. Products of the fetal placenta drive tolerance in the pregnant uterus.

Figure 1

The fetal placenta is directly apposed and in contact with the decidua throughout pregnancy. Placental cells exhibit cell surface molecules and synthesize soluble substances that program a tolerant phenotype in maternal immune cells in the adjacent decidua.