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. Author manuscript; available in PMC: 2009 Nov 5.
Published in final edited form as: Behav Brain Res. 2009 May 19;203(2):264–269. doi: 10.1016/j.bbr.2009.05.013

Fig. 2.

Fig. 2

A sex difference and opposite effects of stress on CB1 receptors in hippocampus of males versus females. (A) There was a significant difference in the level of CB1 receptors of males (n = 12) and females (n = 11), with females having lower levels, in unstressed controls (two-way ANOVA; p < 0.03). Males (n = 6) subjected to three weeks of unpredictable stress exhibited significantly reduced levels of CB1 receptor protein (Tukey; p < 0.05), whereas females (n = 5) had the opposite response, showing increased CB1 receptor protein (Tukey: p< 0.004, groups sharing the same letter (a–c) are significantly different from each other. Data represent the mean ± S.E.M.). (B) Representative photomicrographs of western blots showing visualization of bands for CB1 receptors. C = control; S = stressed.