Skip to main content
. Author manuscript; available in PMC: 2009 Sep 21.
Published in final edited form as: Neuropsychopharmacology. 2007 May 9;33(4):769–782. doi: 10.1038/sj.npp.1301447

Figure 7.

Figure 7

Basal and cocaine-stimulated (15 mg/kg, i.p.) neurotransmitter levels in the NAC in PNS (for dopamine and serotonin, n = 9 comprised one to three rats from six litters; for glutamate, n = 11 comprised one to three rats from six litters) and control (for dopamine, serotonin, and glutamate, n = 11 comprised one to three rats from five litters) rats following a history of cocaine self-administration. (a) Summary of the NAC placements of the active membrane of the microdialysis probes of PNS (solid lines) and control (gray-filled lines) rats. (b–d) Absolute levels of dopamine, serotonin, and glutamate in the NAC before and after a cocaine challenge. (b′ and d′) Changes from baseline in NAC dopamine, serotonin, and glutamate levels following a cocaine challenge; data shown as mean±SEM transformed to percent change from the basal levels derived from the average of the final three prechallenge samples. Symbol indicates a significant difference between the PNS and control rats (*p<0.05).