Table 2. Reduction of NP-specific Ig titers by injections of MSC-culture supernatants.
Antigen | T -independent | T-dependent | ||||
---|---|---|---|---|---|---|
Antibody isotype | IgM | IgG3 | IgM | IgG1 | IgG2a | IgG2b |
CM2/PBS (no LPS) | 51** | 81NS | 84** | 64** | 51** | 21NS |
CM3/CM1 (LPS) | 58** | 66* | 76** | 69** | 73NS | 91NS |
The percentage of reductive antigen NP-specific Ig titers was calculated from the average of each group injected with CM or PBS (n=8 for T-ID antigen and n=7 for T-D). CM: conditioned medium;
not significant;
p < 0.05;
p < 0.01