Table 3. Genetic associations with DNA methylation levels.

Probe	CHR probe	SNP	CHR	Base	MAF	AA Mean (sd)	AB Mean (sd)	BB Mean (sd)	BETA	SE	R2	T	p	FDR
ALOX12_E85_R	17	rs434473	17	A/G	0.49	0.649 (0.133)	0.493 (0.142)	0.303 (0.151)	−0.173	0.023	0.395	−7.629	2.49E-11	6.37E-03
ALOX12_E85_R	17	rs1126667	17	A/G	0.50	0.315 (0.156)	0.492 (0.143)	0.649 (0.133)	−0.167	0.023	0.380	−7.383	7.86E-11	2.01E-02
ALOX12_P223_R	17	rs434473	17	A/G	0.49	0.686 (0.093)	0.523 (0.120)	0.277 (0.112)	−0.204	0.018	0.583	−11.160	1.33E-18	3.40E-10
ALOX12_P223_R	17	rs1126667	17	A/G	0.50	0.291 (0.127)	0.522 (0.121)	0.686 (0.093)	−0.198	0.019	0.560	−10.650	1.50E-17	3.82E-09
ALOX12_P223_R	17	rs2292350	17	A/G	0.38	0.693 (0.081)	0.558 (0.112)	0.372 (0.180)	0.168	0.022	0.391	7.554	3.53E-11	9.03E-03
MET_E333_F	7	rs38840	7	C/T	0.20	0.835 (0.004)	0.701 (0.062)	0.575 (0.084)	0.127	0.015	0.452	8.567	2.95E-13	7.54E-05
MET_E333_F	7	rs1002399	7	C/T	0.21	0.835 (0.004)	0.694 (0.067)	0.575 (0.086)	0.121	0.015	0.417	7.976	4.87E-12	1.25E-03
KRAS_E82_F	12	rs1566753	6/12	G/T	0.37	0.606 (0.067)	0.518 (0.065)	0.433 (0.074)	−0.087	0.010	0.461	−8.719	1.44E-13	3.67E-05
KRAS_E82_F	12	rs4516942	6/12	A/G	0.37	0.606 (0.067)	0.518 (0.065)	0.433 (0.074)	−0.087	0.010	0.461	−8.719	1.44E-13	3.67E-05