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Formation of SACs requires specific surface proteins. A) S. aureus Newman variants with bursa aurealis insertions in surface-protein genes were examined 5 d following infection of BALB/c mice (cohorts of 20 animals) for bacterial load in homogenized kidney tissues. B) H&E-stained thin sections of infected kidneys were examined by light microscopy at ×12.5 for abscess lesions (arrowheads).
