Table 5. Univariate and multivariate analyses for predicting cause-specific survival in bladder cancer patients treated with chemoradiotherapy.
|
(a) Univariate analysisa |
(b) Multivariate analysisb | ||||
|---|---|---|---|---|---|
| Variable | Category | P-value | Risk ratio (95% CI) P-value | ||
| D1S 171 | Balance or imbalance | 0.2588 | NS | NS | |
| Microsatellite markers | TP73 | 0.0013 | 3382(not calculated) 0.0002 | ||
| D1S243 | 0.0482 | NS | |||
| D1S244 | 0.8444 | NS | NS | ||
| RIZ | 0.6178 | NS | NS | ||
| D1S507 | 0.2756 | NS | NS | ||
| D1S247 | 0.9640 | NS | NS | ||
| ABR | 0.2051 | NS | NS | ||
| D17S1574 | 0.1859 | NS | NS | ||
| YNZ22 | 0.3886 | NS | NS | ||
| D17S1566 | 0.5149 | NS | NS | ||
| ENO3 | 0.7176 | NS | NS | ||
| TP53 | 0.4529 | NS | NS | ||
| D17S520 | 0.2632 | NS | NS | ||
| Clinical parameters | Age | ⩽68 years or >68 years | 0.6652 | NS | NS |
| PS | 0 or >0 | 0.0113 | 2.911(1.31–12.38)0.0047 | ||
| Tumour grade | G2 or G3 | 1.0000 | NS | NS | |
| Tumour stage | Tl or T2 or T3 & T4 | 0.5989 | NS | NS | |
| Recurrence | Yes or No | 0.0027 | 3.467(1.50–14.90)0.0017 | ||
| Response | CR or non-CR | 0.4916 | NS | NS | |
| CDDP doses | ⩽220 mg or >220 mg | 0.3634 | NS | NS | |
| Radiation doses | ⩽32.4 Gy or >32.4 Gy | 0.0486 | 1.655(1.007–2.935) 0.0468 | ||
Used Log-rank test.
Used the Cox proportional hazard test.
CDDP=cis-platinum; CR=clinical response; NS=not significant.