. Author manuscript; available in PMC: 2010 May 5.

Published in final edited form as: J Am Coll Cardiol. 2009 May 5;53(18):1642–1650. doi: 10.1016/j.jacc.2009.01.052

Table 3.

Diagnostic accuracy of coronary CTA for the detection of Acute Coronary Syndrome and Myocardial Infarction during index hospitalization among patients with acute chest pain based on the presence of any coronary plaque or the presence of coronary artery stenosis (>50% luminal narrowing). PPV: positive predictive value; NPV: negative predictive value; LR+: likelihood ratio given positive test result; LR-: likelihood ratio given negative test result; CI: confidence interval

Coronary CTA Finding	Sensitivity (95%-CI)	Specificity (95%-CI)	PPV (95%-CI)	NPV (95%-CI)	LR+	LR−
*Acute Coronary Syndrome*
Any Plaque	31/31(100%)	183/337(54%)	31/185(17%)	183/183(100%)	2.2	0.0
Any Plaque	[0.89–1.00]	[0.49–0.60]	[0.12–0.23]	[0.98–1.00]
Coronary Stenosis	24/31 (77%)	293/337(87%)	24/68 (35%)	293/300 (98%)	5.9	0.3
Coronary Stenosis	[0.59–0.90]	[0.83–0.90]	[0.24–0.48]	[0.95–0.99]

*Myocardial Infarction*
Any Plaque	8/8 (100%)	183/360 (51%)	8/185 (4%)	183/183 (100%)	2.0	0.0
Any Plaque	[0.63–1.00]	[0.46–0.56]	[0.02–0.08]	[0.98–1.00]
Coronary Stenosis	5/8 (63%)	297/360 (83%)	5/68 (7%)	297/300 (99%)	3.7	0.45
Coronary Stenosis	[0.24–0.91]	[0.78–0.86]	[0.02–0.16]	[0.97–1.00]