Table 1.

Parameters used in Markov model evaluating cost effectiveness of Helicobacter pylori eradication treatment for non-ulcer dyspepsia

Parameter	Base case (range used in sensitivity analyses)
Cost of visit to general practice (£)	18* (9-20)
No of visits to general practice per year if dyspeptic	3† (1-12)
Cost of antacid treatment (£)	2.48 (1.68-12.50)‡
Cost of H pylori eradication treatment (£)	37.94 (15.36-39.32)§
Antacid response rate at one year (%)	28¶
Relative risk of dyspepsia with H pylori eradication treatment	0.91 (0.86-0.96)**

Sources of data: 

^*Netten et al.¹⁰ 

^†Delaney et al.¹¹ 

^‡Costs based on magnesium trisilicate 10 ml four times daily for 30 days (base case), magnesium carbonate 10 ml four times daily for 30 days (lower range limit), Gaviscon Advance 10 ml four times daily for 30 days (upper range limit).¹² 

^§Costs based on lansoprazole 30 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1g twice daily for 7 days (base case); ranitidine bismuth citrate 400 mg twice daily, amoxycillin 1 g twice daily, and metronidazole 400 mg twice daily for 7 days (lower range limit); and omeprazole 20 mg twice daily, clarithromycin 500 mg twice daily, and amoxicillin 1 g twice daily for 7 days.¹² 

^¶Mean placebo response rate at one year in systematic review. 

^**Relative risk and 95% CI obtained from systematic review.