Genomic organization of mrdH and mreA in P. putida KT2440. Arrows in the figure indicate the transcriptional orientation of the respective genes. Tn4652 components: tnpA and tnpC (PP_2964 and PP_2965 [transposition function] and PP_2966, PP_2967, and PP_2970 [unknown function]), mrdH (PP_2968 [heavy metal efflux transporter]), mreA (PP_2969 [metal resistance determinant]), and IS1246 tnpA (PP_2971 [transposition function]).