TABLE 1.
Multivariate logistic regression analysis of variables prior to or in the first 8 weeks of infection compared to results from clinical outcomesa (active disease and latent infection)
| Variable | Infection type
|
Odds ratio (95% CI) | P value | |
|---|---|---|---|---|
| Active | Latent | |||
| Age (yr) | 7.88 ± 1.77 | 8.22 ± 1.39 | 1.05 (0.69-1.62) | 0.80 |
| GA (% positive) | 57.1 | 16.2 | 10.81 (2.09-55.96) | 0.005 |
| ESR (mm) | 5.19 ± 8.81 | 2.22 ± 4.88 | 1.09 (0.90-1.32) | 0.39 |
| Weight (kg) | 6.72 ± 1.46 | 7.15 ± 1.63 | 0.79 (0.49-1.25) | 0.31 |
| LPA (fold increase from baseline) | 10.15 ± 10.88 | 17.76 ± 39.6 | 0.99 (0.97-1.02) | 0.75 |
| Gender (male:female) | 33:4 | 31:6 | 0.39 (0.039-3.78) | 0.42 |
| TST (score) | 3.94 ± 0.76 | 3.66 ± 0.71 | 1.09 (0.89-1.33) | 0.39 |
a
Age and weight were measured at the time of infection; GA indicates the GA for M. tuberculosis growth in the first 60 days of infection; ESR indicates the peak ESR in the first 60 days of infection; LPA indicates the lymphocyte proliferation assay of PBMC in response to CFP at 6 weeks postinfection compared to values from the preinfection LPA; and TST indicates the peak TST score in the first 60 days of infection (scoring range, 0 to 5). CI, confidence interval.