TABLE 3.

FACS analysis of myeloid DC from CD11c/HIV^Nef and CD68/HIV^Nef Tg mice

Mouse linea	Mean values obtained for CD11c+ cells ± SDb
	Spleen			LN
	Total no.c	% CD11bhid	% CD11bint/low	Total no.	% CD11bhi	% CD11bint/low
Non-Tg	1.8 ± 1.2	35 ± 4	52 ± 4	0.1 ± 0.1	25 ± 7	55 ± 9
CD11c/HIVNef	2.5 ± 0.8	41 ± 5†d	46 ± 5†	0.1 ± 0.06	39 ± 11*	46 ± 6*
Non-Tg	1.7 ± 0.4	35 ± 1.8	51 ± 1	0.5 ± 0.1	34 ± 4	54 ± 4.4
CD68/HIVNef	1.4 ± 0.3	45 ± 2.8‡	45 ± 1.7*	0.4 ± 0.1	49 ± 3.9†	42 ± 2.2†

^aTg CD11c/HIV^Nef (F98507) and CD68 (F115708) mice (3 to 6 months old) with their respective littermates. Number of animals: For spleen, 12 CD11c/HIV^Nef and 5 CD68/HIV^Nef Tg mice with, respectively, nine and five non-Tg littermates; for LN, eight CD11c/HIV^Nef and four CD68/HIV^Nef Tg mice with, respectively, five and four non-Tg littermates.

^b*, P ≤ 0.05; †, P < 0.01; ‡, P < 0.001.

^cThat is, the absolute cell number (10⁶).

^dGated on total CD11c⁺ DC.