TABLE 1.

Rate constants of 2F5 and 4E10 binding to nominal and biepitope peptide-lipid conjugates

MAb	Peptide-lipid conjugate	Encounter		Docking		Kd (nM)
		ka (105M−1 s−1)	kd (10−2 s−1)	ka (10−2 s−1)	kd (10−4 s−1)
2F5	Nominal	1.79	5.72	3.06	1.05	1.09
	Biepitope	2.34	5.02	2.37	2.32	2.08
4E10	Nominal	1.27	5.97	1.90	8.32	19.65
	Biepitope	5.72	5.99	0.92	4.34	26.95