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Secondary structures adopted by MPER peptides when conjugated to liposomesa
| Peptide | % α-Helix | % β-Sheet | % Randomb |
|---|---|---|---|
| 2F5 nominal epitope peptide | 29.0 | 29.0 | 42.0 |
| 4E10 nominal epitope peptide | 38.0 | 8.0 | 54.0 |
| Biepitope peptide | 33.0 | 17.0 | 50.0 |
Determined by deconvolution of CD spectra of the peptide-lipid conjugates.
Includes beta bends, which are not well estimated by the method employed here (3).
