FIG. 2.

Involvement of STAT1 signaling in the antiviral responses against SINV and VEEV. Neuron cultures from wild-type or STAT1^−/− mice were either untreated (solid bars) or treated with 10 (horizontally hatched bars), 100 (diagonally hatched bars), or 1,000 (cross-hatched bars) IU/ml of IFN-α/β for 24 h and infected with a BHK 21 cell multiplicity of infection of 3 with SINV (A) or VEEV (B). Supernatants titers were then determined for virus yield at 24 h p.i. Error bars are standard deviations.