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Viremia in wt and cathepsin-deficient mice following peroral inoculation. C57BL/6 wt and cathepsin-deficient mice, 2 to 4 days (d) old, were inoculated perorally with 106 PFU T3SA+. Blood samples were collected at the times shown and homogenized by freeze-thawing and sonication. Viral titers in blood samples were determined by a plaque assay. Results are presented as mean viral titers of 9 to 14 mice. The limit of detection was 50 PFU/ml.
