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. 2009 Sep 8;10:420. doi: 10.1186/1471-2164-10-420

Table 2.

Conserved correlated genes are associated with various types of cancer and neurological disorders.

Disease Associated genes References
Schizophrenia BDNF RGS4 NR4A2 Schmidt-Kastner et al. (2006)

Parkinson's disease BDNF PTGS2 SNCA NR4A2 Murer et al. (2001)
Chae et al. (2008)
Pardo and van Duijn (2005)

Alzheimer's BDNF
KALRN
Murer et al. (2001)
Youn et al. (2007)

Polyglutamine neurodegeneration NEFL
BAIAP2
Mosaheb et al. (2005)
Thomas et al. (2001)

alpha-mannosidosis MAN1A1 D'Hooge et al. (2005)

Ophthalmopathy CYR61 DUSP1 EGR1 PTGS2 Lantz et al. (2005)

Epilepsy BDNF DUSP6 EGR1 Binder and Scharfman (2004)
Rakhade et al. (2007)

Depression BDNF DUSP1 Russo-Neustadt and Chen (2005)
Rakhade et al. (2007)

Ischemia BDNF CD44 PTGS2 Binder and Scharfman (2004)
Murphy et al. (2005)

Ovarian carcinoma BDNF ITF2 DUSP1 RGS4 Yu et al. (2008)
Kolligs et al. (2002)
Puiffe et al. (2007)

Breast cancer BDNF FGFR1 CCND2 PLAU SERPINE1 PLAUR MAZ DUSP6
EGR1
KFL10
PTRF
Tozlu et al. (2006)
Koziczak et al. (2004)
Grebenchtchikov et al. (2005)
Cui et al. (2006)
Liu et al. (2007)
Reinholz et al. (2004)
Levea et al. (2000)

Lung cancer BDNF ODZ2 CCND2 GFI1 Ricci et al. (2005)
Kan et al. (2006)

Prostate cancer BDNF IGFBP5 PLAUR p75NTR Bronzetti et al. (2008)
Nalbandian et al. (2005)

Pheochromocytoma PCSK1 PCSK2 SCG2 Guillemot et al. (2006)

Endometrial cancer CXCL5 OLFM1 Wong et al. (2007)

Leukemia PKCB1 CCND2 Hans et al. (2005)