Table 1.
Asymmetric Hydrovinylation of Vinylarenesa
| entry | product | conv.b | yieldc | selec.b,d | ee(%)e/conf.f |
|---|---|---|---|---|---|
| 1. |  |
>99 | 97 | >99 | 96, R |
| 2. |  |
>99 | 97 | >99 | >97, R |
| 3. |  |
>99 | 98 | >99 | 99, R |
| 4. |  |
>99 | 98 | >99 | 97, R |
| 5. |  |
>99 | 99 | >99 | 91, R |
| 6. |  |
>99 | 99 | 99 | >97, R |
a
See experimental section for details.
b
Conversion and selectivities determined by GC analysis.
c
Yields determined by isolated mass after column chromatography.
d
Selectivity for the branched HV product.
e
Determined by GC except for 4, which was determined by HPLC.
f
Configuration assigned by comparison to GC and HPLC data with authentic samples (2 and 4). Others assigned by analogy.