Table 3.
Effect estimatesa for target pest classes of agricultural pesticides applied within ½-mi of residences on childhood acute lymphoblastic leukemia, the Northern California Childhood Leukemia Study, California, 1990-2002
Exposure rangeb (lb/mi2) | Exposure: Lifetime | Exposure: First year of life | |||||||
---|---|---|---|---|---|---|---|---|---|
Target pest class | Cases | Controls | OR | 95% CI | Cases | Controls | OR | 95% CI | |
Insecticides | <1 | 123 | 163 | 1.0 | 124 | 162 | 1.0 | ||
1 - 72 | 59 | 52 | 1.5 | 0.9, 2.4 | 38 | 38 | 1.2 | 0.7, 2.2 | |
72 - 3,218 | 31 | 53 | 0.8 | 0.5, 1.4 | 29 | 44 | 0.8 | 0.5, 1.5 | |
Herbicides | <1 | 125 | 160 | 1.0 | 126 | 166 | 1.0 | ||
1 - 57 | 51 | 54 | 1.2 | 0.8, 1.9 | 34 | 39 | 1.3 | 0.8, 2.3 | |
57 - 2,186 | 37 | 54 | 0.9 | 0.5, 1.5 | 31 | 39 | 1.0 | 0.6, 1.9 | |
Fungicides | <1 | 141 | 181 | 1.0 | 138 | 175 | 1.0 | ||
1 - 64 | 40 | 43 | 1.2 | 0.7, 2.4 | 27 | 33 | 0.9 | 0.5, 1.7 | |
64 - 2,779 | 32 | 44 | 0.9 | 0.5, 1.6 | 26 | 36 | 0.9 | 0.5, 1.5 | |
Plant growth regulators | <1 | 197 | 243 | 1.0 | 178 | 226 | 1.0 | ||
1 - 13 | 9 | 12 | 0.9 | 0.4, 2.4 | 9 | 5 | 2.5 | 0.7, 8.6 | |
13 - 447 | 7 | 13 | 0.7 | 0.2, 1.9 | 4 | 13 | 0.4 | 0.1, 1.3 | |
Fumigants | <1 | 154 | 202 | 1.0 | 157 | 199 | 1.0 | ||
1 - 549 | 41 | 33 | 1.7 | 1.0, 3.1 | 18 | 18 | 1.0 | 0.4, 2.2 | |
549 - 42,342 | 18 | 33 | 0.8 | 0.4, 1.4 | 16 | 37 | 0.7 | 0.4, 1.4 |
CI, confidence interval; OR, odds ratio.
Estimated by using conditional logistic regression, adjusting for household income.
Moderate and high exposure categories are based on the median pesticide-use density among the controls with density ≥1 lb/mi2.