Table 1.
Population | Genotype Means (95% C.I.)** of Insulin Sensitivity in mg/kg/min | p-value† | ||
---|---|---|---|---|
All | CC= 10.9 (10.6, 11.3) N = 314 |
CT= 11.1 (10.4, 11.7) N = 205 |
TT= 11.1 (9.9, 12.2) N = 40 |
.85 |
Whites | CC= 11.1 (10.6, 11.5) N = 262 |
CT= 11.1 (10.5, 11.7) N = 175 |
TT= 11.8 (10.6, 13.0) N = 33 |
.48 |
African Americans | CC= 10.1 (9.2, 11.0) N = 52 |
CT/TT= 10.7 (9.4, 12.0) N = 37 |
.40†† | |
Parents (ages 32-64, median = 48) | CC= 11.1 (10.4, 11.8) N = 117 |
CT= 11.4 (10.6, 12.3) N = 81 |
TT= 11.7 (9.6, 13.8) N = 14 |
.75 |
Offspring (ages 11-30, median = 18) | CC= 10.7 (10.3, 11.2) N = 197 |
CT= 11.0 (10.2, 11.7) N = 124 |
TT= 10.5 (9.2, 11.7) N = 26 |
.77 |
All regression analyses adjusted for age and sex
95% confidence intervals presented in parentheses next to genotype means
for a 2 d.f. test, except in African Americans
where CT and TT genotypes were combined for analysis due to small numbers resulting in a 1 degree of freedom test