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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2009 Sep 1;8(9):2726–2735. doi: 10.1158/1535-7163.MCT-09-0377

Figure 3. Curcumin inhibits cytokine-induced signal transduction in immune cells.

Figure 3

Figure 3

PBMCs were pre-treated for 5 hours with curcumin (10 or 20 µM) and subsequently stimulated with (A) IFN-α, IFN-γ or (B) IL-2 for 15 minutes. Phosphorylation of STAT1, STAT3 and STAT5 proteins were evaluated by immunoblot analysis. Total STAT1, STAT3 or STAT5 proteins were measured to control for loading.