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Mean (SEM) body weight on male C57BL/6J mice begun on calorie restriction (CR) at 13-14 mo of age. Body weight was significantly reduced in CR mice beginning 4 weeks after initiation of 40% CR phased in with 10% restriction each week (two-tailed t-test comparisons at each week, ps <0.05). Mean (SEM) body weight on male C57BL/6J mice following CR starting at 13-14 mo of age.
