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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Cell Immunol. 2009 Jul 10;259(2):177–184. doi: 10.1016/j.cellimm.2009.06.013

Figure 5. CD28 cannot fully recover primary antigen-specific IgE and IgG1 responses in ICOS−/− mice.

Figure 5

ICOS+/+ (black bars) or ICOS−/− (white bars) mice were sensitized i.p. with ovalbumin in alum and treated i.p. on day 0 with either anti-CD28 or HIg. OVA specific IgE, IgG1, IgG2a and IgG2b were measured on day 14 after sensitization with ova in alum. IgG1 and IgG2b levels were measured at 1:1000 dilution and IgG2a at 1:20.