Table 1.

Multivariate logistic maximum likelihood estimates of segregation models for inheritance of ankylosing spondylitis in family C

	Multifactorial only	Multifactorial+commingled	Multifactorial+Mendelian	Multifactorial+free τ’s	Multifactorial+dominant	Multifactorial+recessive
qA	(1.0)	5.13×10−3	0.68	0.84	0.70	0.97
τAA	…	…	(1.0)	0.0	(1.0)	(1.0)
τAB	…	…	(0.5)	1.0	(0.5)	(0.5)
τBB	…	…	(0.0)	0.0	(0.0)	(0.0)
SuscAA	…	0	7.67×10−30	7.36×10−35	4.41×10−22	8.49×10−55
SuscAB	…	0.14	7.61×10−26	0	4.41×10−22	0.50
SuscBB	0.17	0.14	0.51	0.54	0.56	0.50
ρresid	1.67	8.08	4.00	4.02	4.06	3.87
-2lnL	47.16	32.15	26.38	22.36	26.44	28.13
Akaike’s AIC	51.16	42.15	36.38	32.36	34.44	36.12

Test H₀₁: no major gene effect, χ² = 20.78, df = 3, p = 1.17×10⁻⁴.

Test H₀₂: no transmission of major gene effect, χ² = 9.79, df = 3, p = 0.02.

Test H₀₃: Mendelian transmission, χ² = 4.02, df = 3, p = 0.26.

Test H₀₄: Mendelian transmission and dominant inheritance, χ² = 0.06, df = 1, p = 0.81.

Test H₀₅: Mendelian transmission and recessive inheritance, χ² = 1.75, df = 1, p = 0.19.