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Total ion count (TIC) chromatographs of tryptic digests of untreated (a) and BCCL1 treated (b) HIV CA. Un-fractionated cross-linking reaction (top), unbound fraction (middle), and eluted fraction (bottom) from a 96 well streptavidin coated plate were analyzed by nanoLC-ESI ion-trap FT-ICR hybrid mass spectrometry (LTQ FT, Thermo Finnigan).
