TABLE III.
Association of MBL2 genotypes on CNS progression-free survival in children: Whole cohort
| MBL2 genotypes compared | RH (95% CI), P value |
|---|---|
| O/O vs A/O* | 2.24 (1.00-5.01), .045 |
| Adjusted† | 2.77 (1.13-6.79), .03 |
| Adjusted‡ | 2.51 (1.09-5.81), .03 |
| Adjusted§ | 2.37 (1.02-5.50), .04 |
| O/O vs A/A* | 1.46 (0.98-2.16), .054 |
| Adjusted† | 1.63 (1.06-2.51), .03 |
| Adjusted‡ | 1.38 (0.92-2.06), .12 |
| Adjusted§ | 1.58 (1.04-2.41), .032 |
| O/O vs A/O+A/A* | 2.15 (1.00-4.64), .04 |
| Adjusted† | 2.74 (1.19-6.33), .02 |
| Adjusted‡ | 2.04 (0.94-4.46), .07 |
| Adjusted§ | 2.44 (1.10-5.39), .027 |
Unadjusted.
Adjusted for CD4+ lymphocyte count, HIV-1 RNA, treatments, race, and sex.
Adjusted for CCR5-wt/Δ32, -59029-G/A, CX3CR1-249-V/I, -280-T/M, and SDF-1-180-G/A.
Adjusted for MBL2-H/L, MBL2-P/Q, and MBL2-X/Y.