Table 2.
Comparison of baseline profiles between groups A (24 weeks) and B (48 weeks)
| Group A | Group B | P-value† | |
|---|---|---|---|
| Patients, n | 55 | 53 | |
| Gender, male/female (% male) | 35/20 (64) | 33/20 (62) | 0.883‡ |
| Age (years)a | 56.9 ± 11.3 | 55.2 ± 13.1 | 0.473§ |
| Weight (kg)a | 59.9 ± 11.6 | 64.3 ± 14.3 | 0.087§ |
| Naive/re-treatment | 48/7 | 49/4 | 0.374# |
| Fibrosis staging, n (F1/F2/F3/F4) | 26/12/2/0 | 22/10/4/1 | 0.558‡ |
| Grading, n (A0-1/A2/A3) | 28/11/1 | 16/20/1 | 0.097‡ |
| Genotype, 1/2 (% genotype 1) | 9/46 (16) | 6/47 (11) | 0.580# |
| HCV RNA (kIU/ml)b | 190 (35–1660) | 120 (38–580) | 0.282¶ |
| ALT (IU/l)b [7–42]c | 70 (37–117) | 59 (36–120) | 0.813¶ |
| γ-GTP (IU/l)b [5–50]c | 43 (26–78) | 63 (28–116) | 0.242¶ |
| Neutrophil count (/μl)a [1000–7500]c | 2936 ± 1047 | 2859 ± 1088 | 0.711§ |
| Hemoglobin (g/dl)a [13.5–17.5]c | 14.1 ± 1.0 | 14.1 ± 1.3 | 0.943§ |
| Platelet count (103/μL)a [150–400]c | 177 ± 47 | 181 ± 81 | 0.793§ |
ALT alanine aminotransferase, γ-GTP gamma glutamyl transpeptidase
†Comparison between groups A and B
‡Chi-square test
#Fisher’s exact test
§ Unpaired t-test
¶Mann–Whitney U test
Data are a mean ± SD or b median (interquartile range), c normal range