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. Author manuscript; available in PMC: 2009 Sep 22.
Published in final edited form as: Biometrics. 2009 Feb 4;65(3):822–832. doi: 10.1111/j.1541-0420.2008.01176.x

Figure 4.

Figure 4

P-values from the ALS data analysis around the most promising SNP reported in Schymick et al. (i.e., SNP rs4363506 with location indicated by the arrow). The p-values are presented on the scale of negative logarithm of base 10, and the horizontal lines indicate the Bonferroni genome-wide threshold. Upper panel: p-values of the HS method based on 3-SNP haplotypes (solid line with filled circle) vs. p-values of the SNP-2 method (dotted-dashed line with open triangle). Lower panel: p-values of the HS method (solid line with filled circle) vs. p-values of the HAP method (dashed line with open circle). The “x” signs indicate the p-values of the VC method.