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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Pharmacol Res. 2009 Mar 17;60(1):50–56. doi: 10.1016/j.phrs.2009.03.004

Table 2.

Statistical indexes of CoMFA model based on seventeen competitive inhibitors and estradiol-17β-glucuronide.

CoMFA
PLS statistics
q2 (leave-one-out) 0.615
q2 (five-fold) 0.578
r2 0.966
S 0.164
 F 133.7
 Optimal components 3
Field contribution (%)
 Steric 70.2
 Electrostatic 29.8